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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb151d3ea141e586942ecc244bc3c5b2e26137881f264909177712870c470598' 
  AND token = 'XWnKWr7vaaI8AK3HJn02bpgOewH4KUsY2EfxFLw2zuQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}