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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df45b39c1b7833e9a17548f6e78a9ea380442506fd84c5edacece2f8c4b0bf2d' 
  AND token = 'diqJC7RI4JZTNH9COFZi5NniURNKtl4upLglHtaDXVA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}