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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2572e51b63811514b515c068db0eeeefc11b7f80aa4df43159d863f722b8a0d' 
  AND token = 'pq5EXwqJ/4GFvOuWH92ZqR9LpfV3ksrw4nMxdtMlYw8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}