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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e15f87f1c119d7f0216f42f69245395efae5931810153de110efb450b769ded5' 
  AND token = '8xqN0wCauT99OvxCTVaUPvEXvsrEI0LYl6gafSwF5b0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}