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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd899f53d6ff8273a8f03b46cb7ec712dc0a6103c418b3f5ed766155f6a3fb2ef' 
  AND token = 'RS6Wpq2p+oDQbsvVJ8cmox6xk2LWkDXiMjY5jGOXFJM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}