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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dcdb4f1c8f98c99a080fb51601456cbd9b31b2af191ee56521d0c1453b7c2bb4' 
  AND token = '851+UHUma8/Zlk9Y1ja0U/DSjDE0eLXuU5uR0GJmiSI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}