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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df6bcb15caf79361019e6eaf3afd88bae2f76ba6eefac744a8461115351a2a90' 
  AND token = 'jVUrRiFoei9Vq0VlDPoXHuFX/k9xH2ap1xSBe53kdSY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}