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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9cc0777d6532137e57c3c1524a45c8d01b5586e1b951c7f841eeccddad5240ac' 
  AND token = '5JExz9D42NEYYMc7A3FZ+2TnFWaAnYhBdC/WkrtycDE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}