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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '582b2c4ba4c4d22f262e753d273c79304f44e1388947c1cf1bc3338e1e12aea0' 
  AND token = 'q5dWhriKpfuifkiYvjeKBhpP3a4ZXMIq0aGgjYDJG3o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}