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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a037437ce14c120dd4296c1fc072a4860ab66c2a46d519d75f2261cf8b54e810' 
  AND token = 'FiYIRWR5IZ7aqEId9f2h5aI/DbGImQOIHbrcPq1BKcA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}