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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee3d3c0395c0d8ad34b56e23687d5608d4b8e4288da558f422189cc2a1e45427' 
  AND token = 'TAFE1xlrld8STf+aoqDWp1iYmoeY8WFkvuKx95443ho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}