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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e0f687904f3aaa5f957c8a767be58bf39689f1e3740e92b1c6b83ab2a430ab4' 
  AND token = 'JOh0SYI4bIuqIim8ZEuwT5z8AjGfiE8lM/G1S887FzI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}