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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e5a027c70ee8711024e827c857107f76705eb1dc4f82a0e73f5e1837044695a' 
  AND token = '6QB9ZzguZUVnVJn1fwxk1Hx0+0nR32TUV3tx9AQ30Lc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}