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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3966278b71e6470eaa0b251ef8f34284d92a6ecf207a5055c731a6863d146768' 
  AND token = 'ysbZO3uBMxpTqHZuP7bRpZDCDtNk1hSnwKGi9Uu5EOs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}