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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da39d777027274d39ed013eb3171cd76375faa82ee2b39236b5fdeb0444711a1' 
  AND token = 'zzOL4P6G2DtzfuGU3hzK7UT3m8KHbWQv5ftEKB7/9xE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}