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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45ad4645b3c969b96eaaab6f40091a7ad6885b8cee08aadeb60de5deac740011' 
  AND token = 'XASvZcmTvESDSd5E4rXex4t4O36VWFvXOVv/71nDWIU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}