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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e193d3dda4f02beac8c4e49cb78149972eccf3d1c337fc1eb8c48b5eb5e3361' 
  AND token = 'CF4VoB5uc3O4TNszOkeio1GjjuddqbaK97nxjI4VhJU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}