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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4ac1a2b7f48ad64ab325940ee194c1e7a07d371a23f6e2f7564a9d495a45d86' 
  AND token = 'REo2ZAVm2tGVRSfNql7cknpElHy+5rXRPH97RaV454g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}