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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3c2aae771e6ff6e801a67d858cc2dad02bce5b632b2a9cf7c7d4660429c4178' 
  AND token = 'qyTfgnZy8hu1lpxCSLa2H4U7rgngjmyY5/TtXcdvxtE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}