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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25d311fa7a523982ce3373263ec0ebe5a791c43a40f07ced6e237db153442b4a' 
  AND token = 'qsL45l9WrcgJUf0xBeRpjvIHaSsqMAsY8ldxJpiy1w8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}