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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '140215dfddf6b28b0847b5dd8b355f25a726175b908b3890172e5b785ef78401' 
  AND token = 'Q2VGMK2jFLkt6hIemYbnoXe7kpY49VlXDJBt127WIBs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}