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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa269963cdcb0932cc2eaeac603a253038f7c58aa00738a47ab57b57c4300fee' 
  AND token = 'Up1cqZ7g0XPkJn5UJuXQ4RJwTAWHM6Kiahm2NpLog50=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}