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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '160a67298a96af3c952d0062cc389d270df79cfb01e0ccb40c05f428a7375e16' 
  AND token = 'yd8+QU7aJoylL/Ex4E1ZLS7G7qgzayvv3mmups4yGR4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}