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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '622f602b49acc5e60fb9f103750583a505f01590cb8c8c694c2e59b3705af953' 
  AND token = '7Pog7QweXUPVeT9vhZ1/A3SpurmUZyiUh62h6wlyFlE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}