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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '599ea1880c7ec2937eeae79f372af924678224e69d22623b5d009d47ff43c5cf' 
  AND token = 'OKO8oSCpRgixqtt9ocCQDuMjcrChTk/OboCcmqFQFeY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}