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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46465c0d167bc9d1ef29507f8def9d02e63b4cc55dfbaec11d9bcd1c4f7a3f5e' 
  AND token = 'ROV4jnfbRYEG4ROzrymJj2f6wKxW3k8JiLqvj/QAPfo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}