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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '737e8c38b8b89e4a991383fa6f02af7403f7529156168c06bfc6b1fd37b74875' 
  AND token = 'SPqxodUKRbXOdlWyY2bzk6HqtFuq4kPOVhxAM/6Yknk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}