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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee494a7ed8ac13a6a2f7c742a34ff8600b174979cb265bf74fdd389b6000b570' 
  AND token = 'CHFoB3eTz74eiUOXWZa+N4BV9FkuUtRdW3zuLkOMMoc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}