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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a7194f8d70b22e72300006e3f0e94599aeb7b3c8178b3b44b722787d781a722' 
  AND token = '3btDv/DmdwMjGA+7T63ZsaFSIFjR8oFpoWYzn0MDGxw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}