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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a4870459729c59cd70c70b59a78354d765a9168fba791d852d8aab57042f317' 
  AND token = 'Tks6K22g9nrEJSWosybVmc0iTFhW4xBBXl432NHAHQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}