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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1d11d0b944a9e3172a808155040b9ec3c61750d78276bb587340bfceb8e7e49' 
  AND token = 'I/t9ftZP1wisMFmsEZR9Tn2OuiwPX1piuxnYGGWPaQA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}