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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da4c77453e97432184762667155d470abd5e3d7bcee5e9ba621ee434ca1d9894' 
  AND token = '2xrtVmqxYS+xeISIkKqlDOLdxg22zvCLde6xRaIWcRk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}