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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfe556fd625b2cb6149b906006df96af271f66a727eca80a43af561bc16a1004' 
  AND token = 'pKMs0Wa8zjGQmVdgUQYY3/bZlkZ8MU6Tdk88FXTjKKE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}