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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c46d35897048c5479e07468b87344769af439600a38e955805f96ce0c7086849' 
  AND token = 'siJu/O59mm3IWl00owBhv+VbJfMPFzbS4MaEk/59gLs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}