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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b46edfc3e9a7180cec73f5fe543284f2379a3e9a2cb3702c2153641f482594e' 
  AND token = 'QxKG7xml4t5P+eyZaAugUTjXSdhyU4/c9x8LOqoma8E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}