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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ceaf41d37bef12a761ccd56a5347cc00afce5fea13c9b0d58b05375f48789b1d' 
  AND token = 'H9gUpAkWUahtBa1LymUbvlI3OV3lQ6lrhDr8aqqm/po=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}