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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5cdd5968e9fec503f4536e4176e790196250cc34b4cb772cf8b33989ecbf1fe' 
  AND token = 'E7yxaCWUlks0DhpfTABR+UsB/JtPeyoNVKCxD77GK7U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}