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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df8271d1534beb5a2e6a75ec311987507f5f5a48088a03b5e7a7b038db660777' 
  AND token = 'GXq9fEibrykfKhxRmx8qU+uosRR0d+sM/0OVnhCWe0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}