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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '006622b070305110598780173a419523f2ca61f0c3e3e25bc36ec25e2e9ba3be' 
  AND token = 'ctg7ZtNKOQQgcEWFuFS3zUwM1NWbcwk/1FH11HXAEnE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}