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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd424a77ba39557f79f14857d25e6d16fdec954c3adcd72ed43d9af95912a8c9f' 
  AND token = '5OHedlehFuJGVCfTS72q6Q38qvEvY4PfA4ceTgitCig=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}