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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '078d8b6708001987b17908a5ea5416ddcb9d9d0e9c792f8e99c6cc13f0fe903c' 
  AND token = 'qkTBUqL5yMg4WbQdJnOn+BaFwy01/hl2b/qrfWOe61A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}