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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e099fedbde50988732be77fbc43a3e4f1063420484560a90cf58b81bf0afd06a' 
  AND token = 'PMagGcw1gotT1Z/YMHeHaEWvmDGzgB5RowUsSK9bLY4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}