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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5a3bc5201999d5fd32fba7d75a655f51e8c6400a04d42ac6e1d411b0dd86b32' 
  AND token = 'G53jS+hcdIx9eN+ohdGXSd6Gj0ATxCbi8cAay7NvviM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}