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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f80ecc3afd0d9a21e5313e88a2e077efe998dfeb5f9e0f7b1be85e4751b8731' 
  AND token = 'sOPC5157O4c0atFY6hSHZY2AdtOUsz+q7sygz+5Y/0E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}