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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c049e86b774fcc798f66d24318757dc46040998d26a76c8fe817944dbd95560' 
  AND token = 'IZGfC6eh8ELHST1nxbB4FwDwUzQtcpXPH8UTgh3Wt34=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}