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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5cfd1250a739c6567e5a99097397705af6025b4b41012c8a2ce599fac70e346' 
  AND token = 'bDxA9s0zsXfHw7f23VjXzY6IgrlAZuHMuMBd/7QYdvs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}