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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b617c4b0063623483d8e04ea27c2c29862fbb068f671e88261d2462ff1f95bc' 
  AND token = '1G8NyKvWQEOFnTXv7REcQPj5BB/LHTQSpC9GZZS6UNA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}