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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0c17e3dcb01b8d4f7e955158e767d4307a3d7d35df1384bc99967baf53d795a' 
  AND token = '4Kr6oN6zXwnPaGqkojtUPEztYgTjiEnhBTa5Lhl9NQg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}