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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef96d9a3500a1f59cd1bac1102804009fae10457f0c698421bd67880cfc45f34' 
  AND token = 'FRQj1qu0vqN2RkNAb2yWq3SGSW1m+ROTIxkj4uxwlL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}