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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b16bb589cf1bc78762d91b5c6730aa974395ca0ea509588145c83b3a15d065a' 
  AND token = '7JBkadi/BNqVOiojKEbq0i4rPT5nQWqgWVWgurD7Glo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}